from The National Pulse:
A popular form of contraception used by millions of women across the world has been linked to an increased risk of a rare brain tumor.
Recent research published in the British Medical Journal (BMJ) suggests a connection between the use of injectable medroxyprogesterone acetate — a type of progestogen used by roughly 74 million women globally for birth control — and the increased risk of meningioma, a brain tumor that affects the membranes covering the brain and spinal cord.
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While usually benign, meningiomas potentially lead to serious complications due to their location. The study, carried out by French researchers, used data from the French national health system. It examined nearly 20,000 women who had undergone meningioma surgery over a decade. Analysis of the results highlights a 5.6-fold increased risk of meningioma associated with the long-term use of the injected contraceptive.
The researchers noted that given the injection’s 74 million global users, “the number of attributable meningiomas may be potentially high” in countries where medroxyprogesterone acetate is popular.
Pfizer manufactures two different medroxyprogesterone acetate injections under the names Depo-Provera and Sayana Press. “We are aware of this potential risk associated with long-term use of progestogens and… are in the process of updating product labels and patient information leaflets with appropriate wording,” the company said in a statement following the study’s release.
From 1978 to 1992, Depo-Provera was banned as a contraceptive in the U.S. due to health concerns.
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