by Mary Beth Preiffer, 2nd Smartest Guy in the World:
Medical pioneers are putting their Covid treatment expertise to new uses. For two cancer patients, that meant ‘complete clinical response.’
John Ross receives his first chemotherapy infusion for advanced colon cancer. He suffered immediate side effects, including numbness and burning in his feet, that may be permanent. Apart from his traditional care, he took a protocol that included ivermectin and other treatments. (Photo provided by Roxanne Ross)
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With this article, I begin what I hope will be a series of reports on the use of inexpensive generic drugs for the treatment of cancer. In one of the few good things to come out of the SARS-CoV-2 pandemic, a growing number of physicians who pioneered effective early treatments for Covid-19 is now attempting to learn if safe, off-patent drugs can also work for cancer. So far, results are promising for drugs like ivermectin, mebendazole (2SG: fenbendazole is identical to menbendazole, save for one molecule that was altered solely to increase BigPharma profit margins), and metformin, and supplements like melatonin.
I will write about this emerging movement from the the conference in Phoenix of the Front Line Covid-19 Critical Care Alliance this weekend, where cancer care will be highlighted. (I’m on a panel on censorship Saturday; join me there or watch afterward online.) Here now is the story of one patient and what it may mean for others.
John Ross was fifty-one years old when he was diagnosed, after more than a year of discomfort and growing unwellness, with Stage 3B colon cancer. A three- to four-inch tumor had almost completely blocked and broken through the organ wall; his surrounding lymph nodes were enlarged and presumed cancerous.
In May 2023, Ross started the traditional treatments offered by mainstream medicine—simultaneous radiation and an oral chemotherapy. He did not tell his mainstream cancer doctors that he was also taking, among other things, the repurposed generic drug ivermectin. The drug was famously—and wrongly—vilified as a horse medication during Covid, though it was in reality a Nobel Prize-winning “wonder drug” with huge untapped potential.
Ross and Dr. Mollie James, a functional-medicine physician who oversaw his nontraditional treatment, are modern-day medical trailblazers who might change the way cancer is treated. If they and others in a growing effort are successful, cancer care will be less painful, more affordable, and—the greatest hope—more effective. Practicing in a suburb of St. Louis, Dr. James had used ivermectin and other therapies to successfully fight Covid-19. (I wrote about her treatment of her brother in January of 2022.) She is now taking what she learned in the pandemic and turning it to cancer.
In his quest for the best care, Ross, who lives in Prescott, Wisconsin, went to two major cancer centers in the Midwest. He underwent a battery of blood draws and diagnostic tests and consulted at least a dozen physicians. But only Dr. James found and treated, he said, a low magnesium level, a Vitamin D level that was acceptable but too low, Dr. James believed, for challenging cancer, and, most critically, severe thyroid dysfunction. Nobody had tested for this, he said.
“I don’t know how you are standing here today—I’ve never seen blood this bad,” Dr. James told Ross after his thyroid result came in. First, she said, “I want to get you as healthy as possible before treatment.” Starting three weeks before radiation and chemotherapy, Ross began, along with ivermectin, infusions of high-dose Vitamin C and glutathione; major auto-hemotherapy, also called ozone therapy; and hyperbaric oxygen therapy, along with supplements like high-dose melatonin.
In the ensuing nearly six weeks of radiation and chemotherapy, oncologists, and others caring for Ross remarked repeatedly on how well he was doing. “Even the (radiation) technician, at the last week of treatment, made comments how this is so abnormal to have somebody that wasn’t dealing with any of the burns or anything like that,” including hair loss, Ross recalled.
The clincher, however, came in Ross’s MRI and CT scans in July of 2023. After twenty-eight radiation and chemotherapy treatments and nearly three months of the ivermectin protocol, “Ninety percent of his tumor had turned fibrous, meaning into scar tissue,” Ross’s wife, Roxanne, told me. “And the lymph nodes were half the size,” John added. An oncologist’s report called that an “excellent response.”
Dr. James has seen this outcome twice in almost identical colon cancer cases. Both were men in their fifties with advanced lower colorectal disease. One patient, John Ross, went the traditional route as well as taking the path offered by Dr. James. The other patient, who declined an interview for this article, rejected mainstream medicine and went with ivermectin and assorted other therapies.
The outcome for both, Dr. James said: “Complete clinical response with no surgery.”
The Possibilities
Two years before Covid, researchers analyzed published data that strongly suggested ivermectin could be repurposed, namely put to another off-label use, for cancer. In about twenty laboratory studies, ivermectin was found to inhibit cell proliferation and induce “apoptosis”—cell death—in cancer cell lines of the breast, prostate, ovary, head and neck, colon, and pancreas. In six studies in mice, the drug was effective against glioblastoma, leukemia, and breast and colon cancer. Based on these studies, predictions were made that ivermectin could be employed safely and soon.
“The in vitro and in vivo antitumor activities of ivermectin are achieved at concentrations that can be clinically reachable based on the human pharmacokinetic studies,” stated the 2018 article in the American Journal of Cancer Research. “Thus, existing information on ivermectin could allow its rapid move into clinical trials for cancer patients.”
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