by Geert Vanden Bossche, Trial Site News:
The debate and tension over the efficacy of the Covid-19 vaccines are flaring up. Comparative assessments of vaccine-mediated protection from infection, disease, hospitalization, and death in vaccinated and unvaccinated people are all over the place, with results ranging from convincing evidence of benefit to compelling proof of failure depending on the source of information. Those who’ve become addicted to these comparative statistics seem to forget that gauging the success of human intervention in a pandemic is about measuring success in a dynamic phenomenon and that snapshots taken under certain conditions/settings do not provide information about the overall evolutionary trend and likely health outcome of a pandemic. The latter can only be monitored by measuring temporal changes of parameters that are relevant to public and individual health.